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Bioinformatics Role in Research Work

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Bioinformatics helps in biological research. It is age of bioinformatics. During the experiments we tackle with large data. It is very difficult, to summarized and recall the data. We used computreianal techniques to save and recall the data. With the advancements in experimental protocols, now we have several next generation instruments and techniques available for obtaining digitalized biological information on genes and proteins etc.

In today’s world, when a biologist performs an experiment in the wet -lab, he or she in fact produces digital data which is continuously being stored on computer disks. The data may include text, numbers, symbols or images. Due to advancement in instrumentation used in biological experiments, data is being accumulated at exponentially increasing rates. For example; genome sequences in genome databases are doubling every few year Human brain is limited in recalling information from memory. First, we have to commit all information to our memory followed by its recall. To overcome our ability to memorize and recall, computers can come to our rescue. This is because computers have an infinite ability to recall this information and process it quickly towards results. Bioinformatics primarily deals with digitalized biological information as well as data reported from biology experiments. Computational methods, data processing techniques and algorithms are employed in addressing the following issues:

  • Storage of data
  • Organization data
  • Analysis of many experiments
  • For representation of biological informatio
  • Bioinformatics can help in assembling DNA sequencing data.
  • It can help in gene finding (markers).
  • Gene assembly can be performed using bioinformatics tools (nucleotide alignments)
  • It can help transcribe the gene data to RNA data
  • Also, databases can be generated from such data.
  • Evolutionary relationships between different organisms can be derived from data.
  • Evolutionary distance among species can be computed by using bioinformatics tools.
  • Phylogenetic trees can be constructed to find relationships between species.
  • Ancestry can be better understood between several species and organisms.
  • Bioinformatics can help us in decoding protein sequences.
  • It can also help us in understanding protein structure.
  • We can also understand post translational changes in proteins with the help of bioinformatics.
  • We can better understand the protein-protein interaction in different biological reactions.
  • It can also help us in generating databases of these sequences and structu
  • Bioinformatics can assist us in modelling regulatory mechanisms in gene and protein networks.
  • Such models can be analyzed to identify the key regulators in these networks.
  • Moreover, the models can help evaluate drugs to treat these key regulators.

Bioinformatics can be applied to life in many ways it helps us to understand the sequence and function of biomolecules and their relationships. Recent trends in bioinformatics involve development of personalized therapeutics for cancer and diabetes.

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