Malaria Facts: [Essay Example], 443 words GradesFixer
exit-popup-close

Haven't found the right essay?

Get an expert to write your essay!

exit-popup-print

Professional writers and researchers

exit-popup-quotes

Sources and citation are provided

exit-popup-clock

3 hour delivery

exit-popup-persone
close
This essay has been submitted by a student. This is not an example of the work written by professional essay writers.

Malaria Facts

Download Print

Pssst… we can write an original essay just for you.

Any subject. Any type of essay.

We’ll even meet a 3-hour deadline.

Get your price

121 writers online

blank-ico
Download PDF

Malaria is an acute febrile, mosquito-borne blood disease caused by a Plasmodium parasite. It is transmitted to humans through the bite of the female Anopheles mosquito. As P. falciparum matures the infected erythrocytes adhere to microvascular endothelium, a term coined cytoadherence, they constrain vascular function and reduce perfusion. The extent to which the vital organs are affected determine the clinical pattern and outcome of severe falciparum malaria. [1]

According to WHO, 216 million cases of malaria were reported globally and caused 445,000 deaths, thus effectively passing as an alarming epidemic. As per the latest report of WHO-UNICEF, India is third among 15 countries having the highest cases of morbidity and mortality due to malaria.[2]

Some population groups like infants, children under 5 years of age and patients with HIV/AIDS are at a greater risk of contracting malaria.[3]

Pregnant women, especially primigravid women, are up to 10 times more likely to contract malaria. Gravid women also have a greater tendency to develop severe malaria.[4]

Malaria is considered uncomplicated when symptoms are present but there are no clinical or laboratory signs to indicate severity or dysfunction of organs. Severe malaria typically occurs as a progression of uncomplicated malaria. P. falciparum can cause severe malaria because it multiples rapidly in the blood, and can thus cause severe blood loss (anemia).

Antimalarial drugs are used to to curb various symptoms of malaria as well as eradicate the parasite. Current practice in treating cases of malaria is based on the concept of combination therapy (e.g., Coartem). This regimen offers several advantages, some of them being reduced risk of treatment failure, reduced risk of developing resistance, enhanced convenience, and reduced side-effects.[5] Parasite clearance rates are chief measures of anti-malarial drug efficacy. They are particularly important in the assessment of artemisinin resistance. [6] In the erythrocytic schizogony cycle, artemisinins exert action on a wide range of stages-from ring forms to early schizonts, thus have the broadest time window of anitmalarial actions. [7]

WHO recommends artemisinin-based combination therapies (ACTs) for the treatment of uncomplicated malaria caused by the P. falciparum parasite. By combining 2 active ingredients with different mechanisms of action. The choice of ACT should be based on the results of therapeutic efficacy studies aga inst local strains of P. falciparum malaria.

Fever is the most common sign during an acute malarial attack and can be accompanied by other auxillary symptoms such as headache, diarrhea, abdominal pain, vomiting, and nausea. [8]

The Indian studies on fever and parasite clearance on patients receiving ACT is inadequate, hence this study is requisite for establishing a correlation between the drug being administered and it’s outcome.

Remember: This is just a sample from a fellow student.

Your time is important. Let us write you an essay from scratch

100% plagiarism free

Sources and citations are provided

Find Free Essays

We provide you with original essay samples, perfect formatting and styling

Cite this Essay

To export a reference to this article please select a referencing style below:

Malaria Facts. (2018, December 11). GradesFixer. Retrieved October 28, 2020, from https://gradesfixer.com/free-essay-examples/malaria-facts/
“Malaria Facts.” GradesFixer, 11 Dec. 2018, gradesfixer.com/free-essay-examples/malaria-facts/
Malaria Facts. [online]. Available at: <https://gradesfixer.com/free-essay-examples/malaria-facts/> [Accessed 28 Oct. 2020].
Malaria Facts [Internet]. GradesFixer. 2018 Dec 11 [cited 2020 Oct 28]. Available from: https://gradesfixer.com/free-essay-examples/malaria-facts/
copy to clipboard
close

Sorry, copying is not allowed on our website. If you’d like this or any other sample, we’ll happily email it to you.

    By clicking “Send”, you agree to our Terms of service and Privacy statement. We will occasionally send you account related emails.

    close

    Attention! this essay is not unique. You can get 100% plagiarism FREE essay in 30sec

    Recieve 100% plagiarism-Free paper just for 4.99$ on email
    get unique paper
    *Public papers are open and may contain not unique content
    download public sample
    close

    Sorry, we cannot unicalize this essay. You can order Unique paper and our professionals Rewrite it for you

    close

    Thanks!

    Your essay sample has been sent.

    Want us to write one just for you? We can custom edit this essay into an original, 100% plagiarism free essay.

    thanks-icon Order now
    boy

    Hi there!

    Are you interested in getting a customized paper?

    Check it out!
    Having trouble finding the perfect essay? We’ve got you covered. Hire a writer

    GradesFixer.com uses cookies. By continuing we’ll assume you board with our cookie policy.