This essay has been submitted by a student. This is not an example of the work written by professional essay writers.

Dynamic Mutation and Associated Disorders: Huntington’s Disease

downloadDownload printPrint

Table of contents

  1. Huntington’s Disease
  2. Testing for the Disorder
  3. Conlcusion

Diseases caused by dynamic mutations involve an unstable responsible mutation. Such disorders are characterized by an uncontrolled expansion of a portion of DNA within the diseased gene consisting of repeated units of three or more tandem nucleotides. Generally, there are polymorphic alleles in the genes associated with these diseases.

Huntington’s Disease

This condition is acquired in an autosomal dominant pattern. Huntington’s disease is a dynamic cerebrum issue that causes uncontrolled development, intense subject matters, and loss of capacity to think (perception). The most widely recognized type of this issue, grown-up beginning Huntington sickness, for the most part happens in the thirties or forties of an individual. Early signs and side effects may incorporate crabbiness, melancholy, minor automatic developments, poor coordination, and issue adapting new data or basic leadership. Numerous individuals create continued yanking or jerking developments known as chorea with Huntington disease. Such motions become increasingly articulated as the illness advances. People influenced may experience issues strolling, talking, and gulping. Huntington illness is brought about by changes in the HTT gene. The HTT gene gives directions on the best way to make a protein called huntingtin. In spite of the fact that this present protein’s capacity is vague, it appears to assume a significant job in the mind’s nerve cells (neurons). The HTT change causing Huntington disease includes a fragment of DNA known as a repetition of the CAG trinucleotide. This segment comprises of a progression of three structure squares of DNA (cytosine, adenine, and guanine) that show up in succession a few times. The CAG area is generally imitated inside the gene 10 to multiple times.

Testing for the Disorder

Predictive – Predictive gene mutation screening that triggers the disease of Huntington allows people who know that they are at risk to find out if they will develop HD later. For several therapy appointments, people who want predictive testing generally need to come to a specialist clinic in person.

Prenatal – Prospective parents seek prenatal testing when one parent is diagnosed or found to bear the gene of Huntington’s disease. Prenatal testing will show if the defective gene is inherited by the infant. … If the fetus tests positively, the parents will determine whether to stop the pregnancy

Theory behind the testing – The discovery of the HD gene contributed to a genetic test for Huntington’s disease diagnosis or confirmation. Using a blood sample, by counting the number of CAG repeats in the huntingtin genome, the genetic test analyzes DNA for the HD mutation. Individuals without HD typically have 28 repetitions or less.


Huntington’s Disease is caused by dynamic mutation in genes. Interesting fact that Adolf Hitler was suffering with this disease. It is not a common disease and therefore little studied; research into its treatment and prevention is still ongoing.

Remember! This is just a sample.

You can get your custom paper by one of our expert writers.

Get custom essay

121 writers online


Remember: This is just a sample from a fellow student.

Your time is important. Let us write you an essay from scratch

experts 450+ experts on 30 subjects ready to help you just now

delivery Starting from 3 hours delivery

Find Free Essays

We provide you with original essay samples, perfect formatting and styling

Cite this Essay

To export a reference to this article please select a referencing style below:

Dynamic Mutation and Associated Disorders: Huntington’s Disease. (2022, August 30). GradesFixer. Retrieved March 29, 2023, from
“Dynamic Mutation and Associated Disorders: Huntington’s Disease.” GradesFixer, 30 Aug. 2022,
Dynamic Mutation and Associated Disorders: Huntington’s Disease. [online]. Available at: <> [Accessed 29 Mar. 2023].
Dynamic Mutation and Associated Disorders: Huntington’s Disease [Internet]. GradesFixer. 2022 Aug 30 [cited 2023 Mar 29]. Available from:
copy to clipboard

Where do you want us to send this sample?

    By clicking “Continue”, you agree to our terms of service and privacy policy.


    Be careful. This essay is not unique

    This essay was donated by a student and is likely to have been used and submitted before

    Download this Sample

    Free samples may contain mistakes and not unique parts


    Sorry, we could not paraphrase this essay. Our professional writers can rewrite it and get you a unique paper.



    Please check your inbox.

    We can write you a custom essay that will follow your exact instructions and meet the deadlines. Let's fix your grades together!


    Hi there!

    Are you interested in getting a customized paper?

    Check it out!
    Don't use plagiarized sources. Get your custom essay. Get custom paper

    We can help you get a better grade and deliver your task on time!

    • Instructions Followed To The Letter
    • Deadlines Met At Every Stage
    • Unique And Plagiarism Free
    Order your paper now