This essay has been submitted by a student. This is not an example of the work written by professional essay writers.

Hemophilia a and B as an Inherited Disorder

downloadDownload printPrint

Remember! This is just a sample.

You can get your custom paper by one of our expert writers.

Get custom essay

121 writers online

Download PDF

Hemophilia A and Hemophilia B are inherited in a X-linked patter. Sudden effects of hemophilia include sudden pain, swelling, and warm joints, in the knees, elbows, hips and possibly your shoulders. Common symptoms are blood in stool, blood in urine, internal bleeding or swollen joints. Hemophilia occurs in about 1 of every 5,000 male births. Currently, about 20,000 males in the United States are living with the disorder. Hemophilia A is about four times as common as hemophilia B, and about half of those affected have the severe form. Hemophilia affects people from all racial and ethnic groups.

Hemophilia has been called a “royal disease”. This is because the hemophilia gene was passed from Queen Victoria, who became Queen of England in 1837, to the ruling families of Russia, Spain, and Germany. Queen Victoria’s gene for hemophilia was caused by spontaneous mutation. Hemophilia is a genetic, but rare disorder that does not allow your blood to clot properly, which in turn, can make it hard for you to stop bleeding. This is often caused by an abnormality in DNA that causes substances called clotting factors to operate, abnormally. It is primarily an inherited disorder; the inheritance of hemophilia C follows an autosomal recessive pattern.

The gene that causes the deficiently is not present on a sex chromosome and the condition can affect both genders equally. For example, if a female who inherits one affected X chromosome, it becomes a carrier of hemophilia. She can then pass it on to her children. A female carrier can sometimes have symptoms of hemophilia, also known as mild hemophilia. The carrier of the affected X chromone can also lead a full life but they have a clotting level between 30% and 70%. The most they can possibly suffer is heavy menstrual bleeding. The chance of having hemophilia depends on whether the parents. If they = have hemophilia or are carriers. If the father has hemophilia and the mother is a carrier, sons will have probably have a chance of having hemophilia.

Currently, there is not a cure for hemophilia. But scientists are always trying to find a cure. They believe the answer lies in gene therapy. The chemical “directions” for blood clotting are found on a certain gene in each cell of the body. Thus, males can have a disease like hemophilia if they inherit an affected X chromosome that has a mutation in either the factor VIII or factor IX gene. Females can also have hemophilia, but this is much rarer. In such cases both X chromosomes are affected or one is affected and the other is missing or inactive.

Gene Therapy Helps Patients with Hemophilia. During the clotting process, blood cells become trapped in a fibrous mesh, which is formed with the help of clotting factor IX. Gene therapy is when DNA is transferred into body tissues. It specifically targets cells in the body which are not passed on to the person’s children. Institute researchers are exploring the possibility of treating the disorder with gene therapy. Their strategy is to engineer mesenchymal stem cells, a type of adult stem cell, so that they produce high levels of factor Being able to cure hemophilia with stem cell transplants would be really good.

Remember: This is just a sample from a fellow student.

Your time is important. Let us write you an essay from scratch

experts 450+ experts on 30 subjects ready to help you just now

delivery Starting from 3 hours delivery

Find Free Essays

We provide you with original essay samples, perfect formatting and styling

Cite this Essay

To export a reference to this article please select a referencing style below:

Hemophilia A and B as an Inherited Disorder. (2018, December 17). GradesFixer. Retrieved May 21, 2022, from
“Hemophilia A and B as an Inherited Disorder.” GradesFixer, 17 Dec. 2018,
Hemophilia A and B as an Inherited Disorder. [online]. Available at: <> [Accessed 21 May 2022].
Hemophilia A and B as an Inherited Disorder [Internet]. GradesFixer. 2018 Dec 17 [cited 2022 May 21]. Available from:
copy to clipboard

Sorry, copying is not allowed on our website. If you’d like this or any other sample, we’ll happily email it to you.

    By clicking “Send”, you agree to our Terms of service and Privacy statement. We will occasionally send you account related emails.


    Attention! This essay is not unique. You can get a 100% Plagiarism-FREE one in 30 sec

    Receive a 100% plagiarism-free essay on your email just for $4.99
    get unique paper
    *Public papers are open and may contain not unique content
    download public sample

    Sorry, we could not paraphrase this essay. Our professional writers can rewrite it and get you a unique paper.



    Please check your inbox.

    Want us to write one just for you? We can custom edit this essay into an original, 100% plagiarism free essay.

    thanks-icon Order now

    Hi there!

    Are you interested in getting a customized paper?

    Check it out!
    Don't use plagiarized sources. Get your custom essay. Get custom paper

    Haven't found the right essay?

    Get an expert to write you the one you need!


    Professional writers and researchers


    Sources and citation are provided


    3 hour delivery