Rare Birth Defects: Moebius Syndrome

download print

About this sample

About this sample


Words: 491 |

Page: 1|

3 min read

Published: Jan 4, 2019

Words: 491|Page: 1|3 min read

Published: Jan 4, 2019

Moebius syndrome is a rare birth defect which is caused by the absence or underdevelopment of the 6th and 7th cranial nerves. These cranial nerves are primarily responsible for eye movements and facial expressions. Moebius syndrome can also affect other cranial nerves, such as the 3rd, 5th, 8th, 9th, 11th and 12th. An early warning sign of this condition is usually present at birth (e.g. inability to suck). Additional signs or symptoms might consist of: feeding, swallowing, and choking problems; crossed eyes; absence of facial expressions; inability to smile; high or cleft palate; and speech difficulties. Tongue, jaw, and limb malformations may also be present. Visual symptoms become more dominant as children age (e.g. absence of smiles and facial expressions). 30% - 40% of children who have Moebius syndrome exhibit some degree of autism. There is no cure for Moebius syndrome, nor is there one specific route of treatment. Treatment options such as surgery, physical and speech therapy, plastic reconstructive surgery, and nerve and muscle transfers are strictly supportive and primarily depend on one’s symptoms.

'Why Violent Video Games Shouldn't Be Banned'?

Research on Moebius syndrome has increased significantly within the last 10 years. The Moebius Syndrome Foundation has partnered with the National Institute of Health (NIH), the NIH Office of Rare Diseases (ORD), the National Institute of Neurological Disorders and Stroke (NINDS), the National Institute of Dental and Craniofacial Research (NIDCR), and numerous researchers from 9 countries around the world to expand awareness and clinical research on this disorder. According to the National Institute of Neurological Disorders and Stroke (NINDS), there are a total of 4 studies regarding Moebius syndrome:

  1. Impairments of Oral Language in Mobius Syndrome - Fortaleza University (completed)
  2. Positive Exposure: A Photography and Video Intervention for Individuals with Craniofacial Differences - National Human Genome Research (completed)
  3. Study on Moebius Syndrome and Congenital Facial Weakness Disorders - National Institutes of Health Clinical Center (recruiting)
  4. Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies - Boston Children’s Hospital (recruiting)Sturge-Weber syndrome is a neurological disorder. It is determined at birth by its port-wine stain colored birthmark on one side of the face, specifically the forehead and upper eyelid. This birthmark varies in color from light pink to deep purple. It is caused by an excessive amount of capillaries located beneath the surface of the face, around the trigeminal nerve.

Additional indicators of Sturge-Weber syndrome are abnormal blood vessels on the surface of the brain, loss of nerve cells and calcification of the underlying tissue in the cerebral cortex of the brain. These signs will occur on the same side of the brain as the birthmark. Neurological symptoms, such as seizures, typically occur on the opposite side of the body, from which the birthmark is located. These usually begin in infancy and intensify with age. Other symptoms include occasional or permanent muscle weakness on the same side, developmental delays and cognitive impairment, glaucoma (present at birth or later in life), buphthalmos (enlarged eyeball bulging out of socket) and recurrent migraines.

Image of Alex Wood
This essay was reviewed by
Alex Wood

Cite this Essay

Rare birth defects: Moebius syndrome. (2019, January 03). GradesFixer. Retrieved February 21, 2024, from
“Rare birth defects: Moebius syndrome.” GradesFixer, 03 Jan. 2019,
Rare birth defects: Moebius syndrome. [online]. Available at: <> [Accessed 21 Feb. 2024].
Rare birth defects: Moebius syndrome [Internet]. GradesFixer. 2019 Jan 03 [cited 2024 Feb 21]. Available from:
Keep in mind: This sample was shared by another student.
  • 450+ experts on 30 subjects ready to help
  • Custom essay delivered in as few as 3 hours
Write my essay

Still can’t find what you need?

Browse our vast selection of original essay samples, each expertly formatted and styled


Where do you want us to send this sample?

    By clicking “Continue”, you agree to our terms of service and privacy policy.


    Be careful. This essay is not unique

    This essay was donated by a student and is likely to have been used and submitted before

    Download this Sample

    Free samples may contain mistakes and not unique parts


    Sorry, we could not paraphrase this essay. Our professional writers can rewrite it and get you a unique paper.



    Please check your inbox.

    We can write you a custom essay that will follow your exact instructions and meet the deadlines. Let's fix your grades together!


    Get Your
    Personalized Essay in 3 Hours or Less!

    We can help you get a better grade and deliver your task on time!
    • Instructions Followed To The Letter
    • Deadlines Met At Every Stage
    • Unique And Plagiarism Free
    Order your paper now