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The basic leucine zipper transcription factor C/EBPa, required for the in vivo transition of common myeloid progenitor-to-GM progenitor. Myelomonocyte cell-type features are educed by the ectopic expression of C/EBPa in primary bone marrow cells, lymphocytes or in fibroblasts, where C/EBPa function along with PU.1, as...
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The famous scientist William J. Mayo (1928) once said “The aim of medicine is to prevent disease and prolong life, the ideal of medicine is to eliminate the need of a physician. ” With the the help of technologies available and being developed today we...
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Adenosine 5’-triphosphate (ATP) is a major energy currency of cells and is involved in multiple cellular processes. Monitoring the hydrolytic activity of ATP in cells would be beneficial to understand ATP consuming cellular processes and help in elucidating the mode of action and regulation of...
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Let’s see in detail how this two cellular division differs from each other: Cell division: Mitosis involves only one division that takes place in the telophase phase, while in Meiosis the division occur twice the time and it takes place in Telophase I and Telophase...
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The term “polymer” is composed of two words, (polus, meaning “many, much”) and (meros, meaning “parts”), and refers to a molecule whose structure is composed of multiple repeating units, from which originates a characteristic of high relative molecular mass. The units that make up these...
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It is the cells in tissues that are responsible to mechanical forces. It is now well recognized that mechanical forces play a fundamental role in the regulation of cell functions, including gene induction, protein synthesis, cell proliferation, migration, death, and differentiation, which are essential to...
844 words | 2 Pages
“ Before delving into the adverse effects of changes of pH in our body it’s important to understand what pH is. pH is a measure of hydrogen ion concentration or how acidic or alkaline a substance is on a scale ranging from 1 to 14....
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Functional RNAs are produced through modification of pre-RNA produced from transcription process except bacterial mRNAs which are as such used for protein synthesis without any modification. These series of modification involving removal of introns by splicing are known as processing of RNA. Processing of rRNA...
4007 words | 9 Pages
(3) the amniOl:horionic membrane. Biology Honors Seminar Professor Scott Jan 11 2018 Biology Honors Research Paper The study of life, or biology is a process that has been going on for thousands of years. The interest sparked in humans about who we are and the...
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Introduction/h3> We can consider sickle hemoglobinopathies are due the presence of one or several abnormal hemoglobins with abnormal red blood cell formation under conditions of hypoxia and acidosis. The deformed red cells are rigid, being able to obstruct the small blood vessels and cause hypoxia....
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POLYMERIZATION: DEFINITION: “Process during which large member if small molecules are combine to form macro molecules is called polymerization. Small molecules are called monomers and large molecules are called polymers”. TYPES OF POLYMERIZATION: Polymerization are divide into two types. Addition polymerization. Condensation polymerization. ADDITION POLYMERIZATION:...
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There are 4 major types of blood A, B, AB, and O. What blood you have depends on what antigen is on red cells and what antibody in the plasma; more on that later. Blood type is hereditary and which one you have, depends on...
901 words | 2 Pages
Mitosis and meiosis are two different forms of reproduction in eukaryotic cells. These two processes are similar in some aspects while different in others. Both result in the creation of new cells, but through different methods. Mitosis is a type of asexual reproduction, while meiosis...
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HeLa is a cell type in an immortal cell line used in scientific research. It is the oldest and most commonly used human cell line. Its scientific name is Helacyton gartleri. It came from cervical cancer cells taken on February 8, 1951 from Henrietta lacks...
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Carboxymethylcellulose (CMC), natural polyelectrolytes derived from cellulose by introducing carboxyl methyl group (–CH2COOH), have attracted considerable interests in a wide range of biomedical applications. The molecular weight of the polymer, average number of carboxyl content per anhydroglucose unit, and the distribution of carboxyl substituents along...
2470 words | 5 Pages
More than 90% of of cancer related mortality is caused by metastasis. To develop new therapeutic strategies it is vital to understand the initiation and progression of metastasis. To identify and isolate metastasis initiating tumour-cells scientists developed a fluorescence-activated cell sorting (FACS)-based array. There are...
1936 words | 4 Pages
ABSTRACT: T lymphocytes are key components of the adaptive immune system and play a central role in cell-mediated immunity. Although many subsets of T lymphocytes have been identified and their functions have been characterized, the early development and fate determination of T lymphocytes remain unclear....
1595 words | 4 Pages
Meiosis is a process where a single cell divides twice to produce four cells containing half the original amount of genetic information. These cells are our sex cells – sperm in males, eggs in females.During the process of meiosis one cell divides two times to...
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Although the XXY karyotype has been associated with some forms of crime (Stockholm et al., 2012) most studies have focused instead on individuals who have the XYY or “supermale” mutation, in which males have an extra Y chromosome. In turn males will possess 47 chromosomes...
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According to Gunter Blobel, a biologist and Noble Prize winner, states ‘With a basic electron microscope one is revealed the complex universe of the cell, the basic unit of life.’ Microscopes were designed to magnify structures and small objects by which could not be done...
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Fluorescence in-situ hybridization (FISH) is a molecular diagnostic technique that allows visualization of definite chromosome nucleic acid sequences within a cellular preparation.it involves use of precise annealing of fluorescence labeled DNA probe to complementary targeted sequences. Thus, the genes/sequence of interest could be observed visually...
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Diagnosis The first step in diagnosing a disease is observe signs and special symptoms of this disease symptoms of HL include: High fever Night sweats Persistent fatigue Severe itching Loss of weight without clear explanation(10% of body weight ) Painless swelling of lymph nodes in...
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The apoplastic pathway or also knowned as a non-living pathways provides a direction toward the vascular stele through free spaces and cell walls of the epidermis and cortex. In addition,the apoplastic route allows direct access to the xylem and phloem along the margins of secondary...
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The basic biological unit of all living organisms is cells. Living organisms were diverged into Archaea, Bacteria and Eukarya over a few billion years ago and classified into unicellular and multicellular organisms. Cells are made up of cytoplasm and nucleus, enclosed in a membrane, with...
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An important element of apoptosis induced by stress is that there is a substantial number of cell deaths even for lower doses of radiation. Studies have anticipated for more that 50% of cell to enter apoptosis after a large radiation dose (Haynie and Bryant, 1977)....
1679 words | 4 Pages
HeLa Part Three (Immortality) Essay The year 1973 is when Bobette Lacks, Henrietta’s daughter-in-law, found out that a part of Henrietta was still alive. Bobette was talking to Gardenia’s, her friend, brother-in-law. When he asked her what her last name was he was shocked. He...
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Polymers are large molecules and have the same structural unit repeating over and over and these repeating units are known as monomers. These monomers are attached with each other with covalent bonds and form polymers. Polymers generally consist of high molecular weight and over 10000...
1124 words | 2 Pages
In cells, free radicals are continuously produced either as by-products of metabolism or deliberately as in phagocytes (Cheeseman and Slater 1993). The model of scavenging DPPH radical is especially useful in evaluating chain-breaking activity in the propagation phase of lipid (and protein) oxidation (Manzocco et...
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Movement of solute molecules across the cell membrane into regions of higher concentrations or against a concentration gradient, with the use of metabolic energy input is known as active transport. Binding protein transport systems or ATP-binding cassette transporters (ABC transporters) is a good example of...
1884 words | 4 Pages
Glycolysis – a 10 step biochemical pathway where a glucose molecule (6 C) is split into 2 molecules of pyruvate (3 C). To begin the process 2 ATP must be invested. The energy released from the reactions is captured in the form of 4 molecules...